Position: Senior Scientist Quantitative Biology
Reference: R&D966
Location: Cambridge
Salary: Competitive + excellent benefits
Closing Date: 27th June 2014 
Are you a quantitatively-minded scientist looking for an exciting new challenge? Then why not join our Computational Biology team in Cambridge, UK and apply informatics, mathematical modeling or image analysis to address biological questions for drug discovery. Competencies here cover image analytics, bioinformatics and systems pharmacology and our purpose is to provide quantitative insights to biology. We do so by improving the biological understanding of the target and its engagement, including supporting the identification of molecular mechanisms of action, providing image and data analysis solutions to high content phenotypic screening, and by enhancing AstraZeneca’s ability to prioritize target selection and portfolio projects based on probability of technical success.
About AstraZeneca 
As one of the world's leading pharmaceutical companies, our business is focused on providing innovative, effective medicines that make a real difference in important areas of healthcare. At AstraZeneca, innovation is about more than just research. As one of the world's leading pharmaceutical companies, we’re focused on providing medicines that make a real difference in patient care. That’s we’ve invested in a new research centre and corporate headquarters at the Cambridge Biomedical Campus. It’s a place where you can drive innovation in small molecule and biological research and development, and it’s also a place with a collaborative culture, where you’ll feel valued, energised and rewarded for your ideas and contributions.
As a Senior Scientist Quantitative Biology your skills and qualifications will ideally include:
  • PhD, or equivalent, in mathematics, computer science, statistics, physics, engineering or the life sciences
  • Expertise in one of the core competency areas: bioinformatics (network biology, data analysis, knowledge engineering, text mining, statistical learning), systems pharmacology (mechanistic modeling, dynamical systems, modeling & simulation) or image analytics (primarily cell and tissue based image analysis, high content screening, multivariate data analysis, classification, machine learning techniques)
  • Experience with relevant software tools such as Matlab, R, Mathematica, Perl, Python, Spotfire, Pipeline Pilot
  • Basic understanding of cell biology and human physiology
As a Senior Scientist Quantitative Biology your main responsibilities will involve:
  • Using informatics, modeling or image analytics, you’ll work with drug discovery projects and therapeutic areas to identify and deliver solutions for addressing key biological questions 
  • Building or internalizing, appropriate algorithms and techniques to answer defined biological questions
  • Implementing and developing solutions with appropriate software
  • Build knowledge of computational biology capabilities across R&D
  • Contributing to and leading local and global projects for computational biology
  • Ensuring that results are scientifically robust and documented
Contact:
To apply for this position, please click ‘Apply Now’. 
AstraZeneca welcomes applications from all sections of the community.
An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, national origin, or protected veteran status and will not be discriminated against on the basis of disability.