Protein Chemist-Conjugation-Biotech-£32k-£40k-Hertfordshire-Contract-Antibody-Purification-HPLC-SDS-PAGE-Blotting-Immunoassays-UV-Vis spectroscopy

An Imperial College spin-out company specialising in antibody-drug conjugate (ADC) development for oncology have an exciting opportunity for a Protein Chemist to join them on a 2 year contract. You will have a PhD in Biochemistry or related subject and have significant post-doctoral experience in an applied-academic or industrial setting.

Duties and Responsibilities:

*Perform and document antibody-small molecule conjugation studies using a range of linker chemistry's
*Understand and use excipients to facilitate conjugation and formulation studies
*Perform post-conjugation purification using a range of chromatographic tools and analyses using HPLC, SDS-PAGE/Blotting, Immunoassays, UV-Vis spectroscopy
*Develop, validate and use analytical methods to study ADCs
*Understand and interpret Mass spectrometric and other bio-analytical data

Education and Experience:

*Must be educated to PhD level in bio/chemistry or comparable qualification. However, very experienced post-graduates can make a strong case to apply.
*Need to have up to 6 years post-doctoral experience in an applied-academic or industrial setting.
*Require excellent communication (written and verbal) skills to technical and lay people both internally, with collaborators and at conferences
*The ability to work in a dynamic, multi-disciplinary, collaborative, high-pressure environment is essential
*Require robust and accurate experimental report writing, electronic data management, preparation of SOPs, batch reports and internal/external study reports.
*Demonstrate a high level of attention to detail and work to a high standard
*A track record of publications in peer-reviewed journals is desirable
*An understanding of oncology drug development is desirable
*Must be highly organised and able to liaise with contract research organisations and participate in multiple projects
*Must be highly knowledgeable in technical R&D areas related to ADCs

Please note: This is initially a 2 year contract. There may be the option of extension or a permanent position dependent upon funding.Apply now